HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: TCPD (P39078)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta)
Gene: CCT4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31399574, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0006457 - protein folding GO:0016887 - ATP hydrolysis activity GO:0051082 - unfolded protein binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 528
+	Hs
		437875 HS90B_HUMAN (5-705): 0: 1022: 61.15		TCPA_HUMAN (8-525): 0: 587: 30.97
+	Hs
		431514 HS90A_HUMAN (4-705): 0: 1013: 60.67		TCPA_HUMAN (8-525): 0: 587: 30.97
+	Hs
		437987 HS90B_HUMAN (5-705): 0: 1022: 61.15		TCPG_HUMAN (2-525): 0: 562: 29.68
+	Sc
		543748 HSC82_YEAST (1-705): 0: 977: 100.00		TCPG_YEAST (1-525): 0: 549: 27.05
+	Sc
		366298 HSP82_YEAST (1-705): 0: 968: 95.63		TCPG_YEAST (1-525): 0: 549: 27.05
+	Sc
		543936 HSC82_YEAST (1-705): 0: 977: 100.00		TCPH_YEAST (2-528): 0: 538: 28.20
+	Ca
		804497 HSP90_CANAL (4-705): 0: 953: 82.36		Q59YH4_CANAL (2-527): 0: 562: 29.16
+	Ca
		804551 HSP90_CANAL (4-705): 0: 953: 82.36		Q5AK16_CANAL (1-525): 0: 561: 29.30
+	Sc
		366299 HSP82_YEAST (1-705): 0: 968: 95.63		TCPD_YEAST (1-528): 0: 544: 100.00
+	Ca
		804500 HSP90_CANAL (4-705): 0: 953: 82.36		Q59Z12_CANAL (1-527): 0: 535: 35.09
+	Sc
		543861 HSC82_YEAST (1-705): 0: 977: 100.00		TCPE_YEAST (12-527): 1.47e-98: 310: 35.55
+	Sc
		366392 HSP82_YEAST (1-705): 0: 968: 95.63		TCPE_YEAST (12-527): 1.47e-98: 310: 35.55