HitPredict

Interactor 1: PP2AA (P67775)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16) (Replication protein C) (RP-C)
Gene: PPP2CA

Interactor 2: KCC2B (Q13554)
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)
Gene: CAMK2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045202 - synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 666
+	Hs
		915182 PP2AB_HUMAN (1-309): 0: 528: 97.41		KCC2B_HUMAN (1-666): 0: 710: 100.00
+	Hs
		915261 PP2AB_HUMAN (1-309): 0: 528: 97.41		MARK4_HUMAN (1-569): 2.18e-140: 429: 23.76
+	Hs
		647866 PP2AB_HUMAN (1-309): 0: 528: 97.41		MARK3_HUMAN (1-552): 5.75e-138: 423: 24.49
+	Hs
		930841 PP2AA_HUMAN (1-309): 0: 529: 100.00		KCC1A_HUMAN (12-332): 1.54e-141: 419: 39.25
+	Hs
		159165 PP1G_HUMAN (7-306): 0: 505: 45.96		CSKP_HUMAN (10-308): 1.66e-81: 278: 46.73
+	Hs
		930836 PP2AA_HUMAN (1-309): 0: 529: 100.00		KCC2G_HUMAN (381-666): 5.77e-58: 206: 50.00
+	Hs
		915183 PP2AB_HUMAN (1-309): 0: 528: 97.41		KCC2G_HUMAN (381-666): 5.77e-58: 206: 50.00
+	Hs
		930837 PP2AA_HUMAN (1-309): 0: 529: 100.00		KCC2D_HUMAN (507-666): 1.24e-53: 193: 71.25
+	Hs
		915184 PP2AB_HUMAN (1-309): 0: 528: 97.41		KCC2D_HUMAN (507-666): 1.24e-53: 193: 71.25
+	Dm
		619862 PP2A_DROME (1-309): 0: 524: 93.85		KCC2A_DROME (458-660): 7.25e-45: 169: 52.20