HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: MET5 (P47169)
Sulfite reductase [NADPH] subunit beta (EC 1.8.1.2) (Extracellular mutant protein 17)
Gene: MET5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	37295430, 19536198, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 1442
+	Hs
		437940 HS90B_HUMAN (5-705): 0: 1022: 61.15		NOS2_HUMAN (622-975): 1.77e-64: 242: 17.96
+	Hs
		431587 HS90A_HUMAN (4-705): 0: 1013: 60.67		NOS2_HUMAN (622-975): 1.77e-64: 242: 17.96
+	Hs
		431564 HS90A_HUMAN (4-705): 0: 1013: 60.67		NOS3_HUMAN (640-992): 1.35e-61: 233: 19.01
+	Ss
		137796 HS90A_PIG (4-705): 0: 1012: 60.45		NOS3_PIG (640-1039): 1.63e-56: 217: 16.89
+	Sc
		543130 HSC82_YEAST (1-705): 0: 977: 100.00		NCPR_YEAST (676-879): 2.54e-40: 162: 24.76
+	Sc
		365736 HSP82_YEAST (1-705): 0: 968: 95.63		NCPR_YEAST (676-879): 2.54e-40: 162: 24.76