Protein: ARHGB
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)

Gene: ARHGB, ARHGEF11
Organism: Homo sapiens
Interactions: 72
UniProt ID: O15085

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0001664 - G protein-coupled receptor binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

167078

RHOA
Transforming protein RhoA

9

20

Small-scale

0.975

High

167077

CDC42
Cell division control protein 42 homolog

3

20

Small-scale

0.854

High

167113

ARHGC
Rho guanine nucleotide exchange factor 12

3

17

High-throughput

0.839

High

167085

GNA13
Guanine nucleotide-binding protein subunit alpha-13

3

20

Small-scale

0.827

High

167079

RHOB
Rho-related GTP-binding protein RhoB

3

20

Small-scale

0.821

High

167063

RHOC
Rho-related GTP-binding protein RhoC

2

20

High-throughput

0.811

High

167100

ARH40
Rho guanine nucleotide exchange factor 40

2

18

High-throughput

0.767

High

167107

PKH4B
Pleckstrin homology domain-containing family G member 4B

2

17

High-throughput

0.767

High

167092

MPRIP
Myosin phosphatase Rho-interacting protein

2

20

High-throughput

0.737

High

167108

NEB2
Neurabin-2

2

20

High-throughput

0.737

High

167065

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

7

Small-scale

0.713

High

167053

PLXB1
Plexin-B1

5

19

Small-scale

0.712

High

167057

PAK4
Serine/threonine-protein kinase PAK 4

4

9

High-throughput

0.694

High

167104

TRM61
tRNA

3

1

High-throughput

0.667

High

167118

PLXB3
Plexin-B3

3

19

Small-scale

0.648

High

165122

PLXB2
Plexin-B2

2

20

Small-scale

0.640

High

167116

PAK5
Serine/threonine-protein kinase PAK 5

2

13

High-throughput

0.628

High

167058

ABL1
Tyrosine-protein kinase ABL1

1

19

High-throughput

0.618

High

167061

FYN
Tyrosine-protein kinase Fyn

1

19

High-throughput

0.618

High

167066

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.618

High

167067

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

High-throughput

0.618

High

167072

CRK
Adapter molecule crk

1

20

High-throughput

0.618

High

167075

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

20

Small-scale

0.618

High

167080

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

167081

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

167082

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

20

Small-scale

0.618

High

167093

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

167076

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

High-throughput

0.575

High

167055

MTX2
Metaxin-2

2

2

High-throughput

0.571

High

167059

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

167069

TMOD1
Tropomodulin-1

2

10

High-throughput

0.571

High

167087

AINX
Alpha-internexin

2

18

High-throughput

0.571

High

167090

WDR59
GATOR2 complex protein WDR59

2

16

High-throughput

0.571

High

167097

LONP2
Lon protease homolog 2, peroxisomal

2

2

High-throughput

0.571

High

167105

LRCH3
DISP complex protein LRCH3

2

1

High-throughput

0.571

High

167106

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

2

High-throughput

0.571

High

167109

S10AD
Protein S100-A13

2

3

High-throughput

0.571

High

167117

CING
Cingulin

2

6

High-throughput

0.571

High

167119

PPIE
Peptidyl-prolyl cis-trans isomerase E

2

6

High-throughput

0.571

High

167121

MYO5A
Unconventional myosin-Va

2

6

High-throughput

0.571

High

167089

MZT2B
Mitotic-spindle organizing protein 2B

2

0

High-throughput

0.547

High

167115

COMD9
COMM domain-containing protein 9

2

0

High-throughput

0.547

High

149801

RFXK
DNA-binding protein RFXANK

1

15

Small-scale

0.536

High

167071

ARRB2
Beta-arrestin-2

1

1

High-throughput

0.536

High

167114

TMOD2
Tropomodulin-2

2

11

High-throughput

0.521

High

167094

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

1

0

High-throughput

0.513

High

167110

F124B
Protein FAM124B

1

0

High-throughput

0.513

High

167070

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

167088

TIGD3
Tigger transposable element-derived protein 3

1

1

High-throughput

0.489

High

167054

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

167056

ABCA1
Phospholipid-transporting ATPase ABCA1

1

2

Small-scale

0.479

High

167060

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

167062

PROF1
Profilin-1

1

6

High-throughput

0.479

High

167064

K1C19
Keratin, type I cytoskeletal 19

1

2

High-throughput

0.479

High

167068

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

11

High-throughput

0.479

High

167073

GSK3A
Glycogen synthase kinase-3 alpha

1

8

Small-scale

0.479

High

167074

GSK3B
Glycogen synthase kinase-3 beta

1

8

Small-scale

0.479

High

167084

TRDN
Triadin

1

7

High-throughput

0.479

High

167091

POTEE
POTE ankyrin domain family member E

1

12

High-throughput

0.479

High

167095

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

2

High-throughput

0.479

High

167096

HOOK3
Protein Hook homolog 3

1

16

High-throughput

0.479

High

167099

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

167102

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

167120

DAAM1
Disheveled-associated activator of morphogenesis 1

1

3

Small-scale

0.479

High

71033

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

6

High-throughput

0.470

High

167112

DISC1
Disrupted in schizophrenia 1 protein

1

10

High-throughput

0.457

High

167103

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.445

High

167083

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.437

High

167086

KS6A1
Ribosomal protein S6 kinase alpha-1

1

10

Small-scale

0.408

High

167098

NOA1
Nitric oxide-associated protein 1

2

0

High-throughput

0.298

High

167101

TFB1M
Dimethyladenosine transferase 1, mitochondrial

2

0

High-throughput

0.298

High

167111

DEFM
Peptide deformylase, mitochondrial

2

0

High-throughput

0.298

High


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Last updated: 15 Jul 2024