HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: HOSC (P48570)
Homocitrate synthase, cytosolic isozyme (HCS) (EC 2.3.3.14)
Gene: LYS20

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37295430, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 428
+	Sc
		366565 HSP82_YEAST (1-705): 0: 968: 95.63		HOSC_YEAST (1-428): 5.98e-169: 482: 100.00
+	Sc
		544578 HSC82_YEAST (1-705): 0: 977: 100.00		HOSM_YEAST (4-425): 1.26e-164: 471: 91.71
+	Sc
		367062 HSP82_YEAST (1-705): 0: 968: 95.63		HOSM_YEAST (4-425): 1.26e-164: 471: 91.71
+	Ca
		804488 HSP90_CANAL (4-705): 0: 953: 82.36		Q59TC4_CANAL (1-420): 1.62e-159: 458: 84.09
+	Sc
		411210 HSC82_YEAST (1-705): 0: 977: 100.00		LEU1_YEAST (4-423): 9.39e-121: 366: 16.81
+	Sc
		365552 HSP82_YEAST (1-705): 0: 968: 95.63		LEU1_YEAST (4-423): 9.39e-121: 366: 16.81
+	Sc
		543369 HSC82_YEAST (1-705): 0: 977: 100.00		PYC2_YEAST (1-426): 8.99e-106: 340: 16.63
+	Sc
		365956 HSP82_YEAST (1-705): 0: 968: 95.63		PYC2_YEAST (1-426): 8.99e-106: 340: 16.63