Protein: PRR1
Serine/threonine-protein kinase PRR1 (EC 2.7.11.1) (Pheromone response regulator 1)

Gene: PRR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P28708

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

602348

PHO85
Cyclin-dependent protein kinase PHO85

2

5

High-throughput

0.799

High

364384

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.724

High

441060

KAPA
cAMP-dependent protein kinase type 1

1

14

High-throughput

0.647

High

704671

PRR1
Serine/threonine-protein kinase PRR1

1

16

High-throughput

0.647

High

704690

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

16

High-throughput

0.647

High

578977

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.618

High

704692

YPT32
GTP-binding protein YPT32/YPT11

1

3

High-throughput

0.579

High

704710

CMR3
Zinc finger protein CRM3

1

1

High-throughput

0.579

High

392357

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.575

High

675774

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.575

High

526098

HSP72
Heat shock protein SSA2

2

3

High-throughput

0.552

High

626630

HSP60
Heat shock protein 60, mitochondrial

2

5

High-throughput

0.552

High

704680

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.536

High

704691

ASK10
Activator of SKN7 protein 10

1

1

High-throughput

0.508

High

704706

STE23
A-factor-processing enzyme

1

2

High-throughput

0.508

High

704678

NCL1
Multisite-specific tRNA:(cytosine-C(5))-methyltransferase

1

1

High-throughput

0.501

High

704686

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

704693

PDK2
[Pyruvate dehydrogenase

1

1

High-throughput

0.501

High

575404

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.489

High

358139

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.480

High

455551

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.480

High

704676

KU70
ATP-dependent DNA helicase II subunit 1

1

0

High-throughput

0.480

High

704698

ADD37
Alpha1-proteinase inhibitor-degradation deficient protein 37

1

0

High-throughput

0.480

High

704701

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.480

High

704707

YL257
Uncharacterized protein YLR257W

1

0

High-throughput

0.480

High

704714

TRM13
tRNA:m(4)X modification enzyme TRM13

1

0

High-throughput

0.480

High

657173

GYS1
Glycogen [starch] synthase isoform 1

1

1

High-throughput

0.479

High

704674

ECM32
Putative ATP-dependent RNA helicase ECM32

1

1

High-throughput

0.479

High

704700

TOM1
E3 ubiquitin-protein ligase TOM1

1

12

High-throughput

0.479

High

704704

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

704708

ESC8
Protein ESC8

1

1

High-throughput

0.479

High

704715

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

207365

YB085
Uncharacterized protein YBR085C-A

1

0

High-throughput

0.458

High

599662

STF2
ATPase-stabilizing factor 15 kDa protein

1

0

High-throughput

0.458

High

704711

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

704712

YOR22
Probable phospholipase YOR022C, mitochondrial

1

0

High-throughput

0.458

High

704713

DAD1
DASH complex subunit DAD1

1

0

High-throughput

0.458

High

704717

YD85C
SERF-like protein YDL085C-A

1

0

High-throughput

0.458

High

704718

HUG1
MEC1-mediated checkpoint protein HUG1

1

0

High-throughput

0.458

High

600660

SEC2
Rab guanine nucleotide exchange factor SEC2

1

1

High-throughput

0.457

High

704689

AVT1
Vacuolar amino acid transporter 1

1

7

High-throughput

0.457

High

704695

RCM1
25S rRNA

1

1

High-throughput

0.457

High

704719

VCX1
Vacuolar calcium ion transporter

1

1

High-throughput

0.457

High

523262

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

544058

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

704673

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

704682

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

704683

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.445

High

617971

IRA1
Inhibitory regulator protein IRA1

1

1

High-throughput

0.437

High

704672

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

704684

MLP2
Protein MLP2

1

2

High-throughput

0.437

High

704699

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.437

High

531637

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.261

Low

661768

TOM40
Mitochondrial import receptor subunit TOM40

1

0

Small-scale

0.261

Low

677902

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.261

Low

704675

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.261

Low

704677

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.261

Low

704679

FZO1
Mitofusin FZO1

1

0

High-throughput

0.261

Low

704685

BRE2
COMPASS component BRE2

1

0

High-throughput

0.261

Low

704687

FAR3
Factor arrest protein 3

1

0

High-throughput

0.261

Low

704696

CTF4
DNA polymerase alpha-binding protein

1

0

High-throughput

0.261

Low

704697

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.261

Low

704703

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

314851

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.249

Low

515020

MTCU2
Copper metallothionein 1-2

1

0

High-throughput

0.249

Low

596799

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

0

High-throughput

0.249

Low

704681

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

704688

NU192
Nucleoporin NUP192

1

0

High-throughput

0.249

Low

704694

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.249

Low

704702

CTPP2
Lipid-anchored plasma membrane protein CPP2

1

0

High-throughput

0.249

Low

704705

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

704709

MSC6
Meiotic sister-chromatid recombination protein 6, mitochondrial

1

0

High-throughput

0.249

Low

704716

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025