HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: PPT1 (P53043)
Serine/threonine-protein phosphatase T (PPT) (EC 3.1.3.16)
Gene: PPT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	11805826, 31399574, 37295430, 16554755, 37968396, 19536198, 15766533, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 513
+	Hs
		438021 HS90B_HUMAN (5-705): 0: 1022: 61.15		PPP5_HUMAN (2-513): 0: 521: 37.70
+	Mm
		513680 HS90B_MOUSE (5-705): 0: 1025: 61.57		PPP5_MOUSE (2-513): 2.39e-180: 517: 38.09
+	Hs
		111935 K9JA46_HUMAN (4-705): 0: 1013: 60.67		PPP5_HUMAN (2-513): 0: 521: 37.70
+	Hs
		431681 HS90A_HUMAN (4-705): 0: 1013: 60.67		PPP5_HUMAN (2-513): 0: 521: 37.70
+	Mm
		432427 HS90A_MOUSE (4-705): 0: 1012: 60.59		PPP5_MOUSE (2-513): 2.39e-180: 517: 38.09
+	Sc
		366604 HSP82_YEAST (1-705): 0: 968: 95.63		PPT1_YEAST (1-513): 4.91e-168: 486: 100.00
+	Sc
		543415 HSC82_YEAST (1-705): 0: 977: 100.00		PP12_YEAST (189-492): 1.5e-156: 449: 34.10
+	Mm
		435924 ENPL_MOUSE (3-705): 0: 897: 46.03		PPP5_MOUSE (2-513): 2.39e-180: 517: 38.09
+	Dm
		1249901 Q9VAY2_DROME (3-676): 0: 833: 47.09		Q8T0U6_DROME (144-509): 4.01e-157: 456: 29.22
+	Dm
		819296 Q9VAY2_DROME (3-676): 0: 833: 47.09		PP1B_DROME (191-509): 4.62e-159: 456: 32.52