HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 116
+	Hs
		850556 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		564456 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		545275 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		925171 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		850548 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		263218 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180857 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		925304 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		180807 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		263159 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		564545 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		180804 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		545398 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		564666 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		263209 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180849 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		892393 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		892567 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		263221 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180859 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69