HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030670 - phagocytic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 100
+	Hs
		925304 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		850556 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		564545 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		925171 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		564456 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		263218 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		545275 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		564666 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		545311 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263159 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		892393 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		951017 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		850548 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		850558 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		892567 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		263209 RAC3_HUMAN (1-191): 1.72e-78: 234: 89.01		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		926199 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		951283 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Mm
		892719 CDC42_MOUSE (1-192): 4.69e-77: 230: 68.75		VAMP2_MOUSE (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263221 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56