Interactor 1: A1Z8U0 (A1Z8U0)
Pre-mRNA-processing-splicing factor 8 (Splicing factor Prp8)
Gene: Prp8

Interactor 2: Q9VPL0 (Q9VPL0)
U5 small nuclear ribonucleoprotein 40 kDa protein (WD repeat-containing protein 57)
Gene: DmelCG3436

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRO8NT~WD40, PROCN~WD40, PRP8_domainIV~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0071011 - precatalytic spliceosome
GO:0071013 - catalytic step 2 spliceosome
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 2396
Dm

1 347
+ Hs
+ Hs
+ At
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025