Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: TLR3 (Q99MB1)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 12672806
Identification Methods electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032481 - positive regulation of type I interferon production
GO:0032728 - positive regulation of interferon-beta production
GO:0032735 - positive regulation of interleukin-12 production
GO:0034138 - toll-like receptor 3 signaling pathway
GO:0035458 - cellular response to interferon-beta
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 329
Mm

1 905
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024