Protein: NOS1
Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)

Gene: NOS1
Organism: Homo sapiens
Interactions: 39
UniProt ID: P29475

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001917 - photoreceptor inner segment
GO:0002028 - regulation of sodium ion transport
GO:0004517 - nitric-oxide synthase activity
GO:0005246 - calcium channel regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

713159

DLG4
Disks large homolog 4

3

4

Small-scale

0.877

High

713163

SNTA1
Alpha-1-syntrophin

2

10

Small-scale

0.799

High

269743

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

0

Small-scale

0.788

High

713149

NOS1
Nitric oxide synthase 1

2

9

Small-scale

0.757

High

713175

CHIP
E3 ubiquitin-protein ligase CHIP

4

3

Small-scale

0.698

High

713152

NOS2
Nitric oxide synthase, inducible

1

9

High-throughput

0.691

High

713164

SNTB2
Beta-2-syntrophin

1

9

High-throughput

0.691

High

713166

SNTB1
Beta-1-syntrophin

1

10

High-throughput

0.691

High

713176

RASD1
Dexamethasone-induced Ras-related protein 1

1

1

Small-scale

0.647

High

713168

DLG2
Disks large homolog 2

1

4

Small-scale

0.621

High

713157

DYL1
Dynein light chain 1, cytoplasmic

2

3

High-throughput

0.601

High

713174

DYL2
Dynein light chain 2, cytoplasmic

2

3

High-throughput

0.601

High

713167

KPCD1
Serine/threonine-protein kinase D1

1

4

Small-scale

0.586

High

713153

NAA10
N-alpha-acetyltransferase 10

2

0

High-throughput

0.576

High

713158

CSK2B
Casein kinase II subunit beta

2

0

High-throughput

0.576

High

713161

VAC14
Protein VAC14 homolog

1

2

Small-scale

0.554

High

713155

SOX2
Transcription factor SOX-2

1

0

Small-scale

0.537

High

250057

ADCY9
Adenylate cyclase type 9

1

1

High-throughput

0.536

High

262366

DTNB
Dystrobrevin beta

1

2

High-throughput

0.536

High

713154

UTRN
Utrophin

1

4

High-throughput

0.536

High

713169

CUL9
Cullin-9

1

1

High-throughput

0.536

High

713160

CKAP4
Cytoskeleton-associated protein 4

1

2

High-throughput

0.515

High

713172

ARRD1
Arrestin domain-containing protein 1

1

0

High-throughput

0.513

High

713170

ZDH23
Palmitoyltransferase ZDHHC23

1

2

Small-scale

0.512

High

605506

SYN1
Synapsin-1

1

0

Small-scale

0.480

High

612886

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

711034

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

1

Small-scale

0.479

High

713150

BKRB2
B2 bradykinin receptor

1

1

Small-scale

0.479

High

713151

HSP74
Heat shock 70 kDa protein 4

1

5

Small-scale

0.479

High

713162

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

6

Small-scale

0.479

High

713173

DCA11
DDB1- and CUL4-associated factor 11

1

1

High-throughput

0.479

High

713177

NOSIP
Nitric oxide synthase-interacting protein

1

1

Small-scale

0.479

High

713156

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.458

High

105405

APRIO
Alternative prion protein

1

1

Small-scale

0.437

High

50801

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.279

Low

713165

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

713171

H6ST3
Heparan-sulfate 6-O-sulfotransferase 3

1

0

High-throughput

0.279

Low

64517

ANR62
Ankyrin repeat domain-containing protein 62

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025