HitPredict

Interactor 1: ZASP (A1ZA47)
PDZ and LIM domain protein Zasp (Z band alternatively spliced PDZ-motif protein)
Gene: Zasp52

Interactor 2: LASP1 (Q8I7C3)
LIM and SH3 domain protein Lasp
Gene: Lasp

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	37061542
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0003779 - actin binding GO:0005925 - focal adhesion GO:0030018 - Z disc GO:0046872 - metal ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2194 Dm			1 657
+	Dm
		86343 C1C3E7_DROME (1-443): 3.17e-105: 347: 90.11		LASP1_DROME (1-657): 2.76e-103: 330: 100.00
+	Hs
		1060028 LPP_HUMAN (1753-2192): 2.66e-83: 289: 20.04		LASP1_HUMAN (538-653): 3.97e-23: 101: 35.66
+	Mm
		1143132 LPP_MOUSE (1746-2192): 1.38e-83: 290: 19.39		LASP1_MOUSE (418-655): 5.07e-19: 89.4: 21.58
+	Hs
		1060077 TES_HUMAN (1857-2194): 5.44e-73: 253: 16.62		LASP1_HUMAN (538-653): 3.97e-23: 101: 35.66
+	Ce
		104675 G5EC72_CAEEL (7-471): 9.22e-84: 284: 25.16		SRBS1_CAEEL (361-655): 2.02e-11: 69.4: 12.58
+	Hs
		1311777 TES_HUMAN (1857-2194): 5.44e-73: 253: 16.62		LIMD2_HUMAN (1-60): 2.95e-23: 97.4: 35.00
+	Hs
		1082195 TES_HUMAN (1857-2194): 5.44e-73: 253: 16.62		CSRP2_HUMAN (4-101): 1.32e-17: 83.5: 21.01
+	Hs
		301018 LIMD1_HUMAN (1629-2192): 1.64e-74: 265: 17.24		ABLM3_HUMAN (5-591): 4.23e-12: 71.3: 8.42
+	Hs
		1021712 PDLI7_HUMAN (1774-2194): 2.23e-29: 126: 13.48		MYO1E_HUMAN (64-655): 3.94e-42: 166: 11.59
+	Hs
		596196 LIMS1_HUMAN (2018-2076): 7.83e-12: 71: 33.90		NEBU_HUMAN (68-655): 1.48e-52: 198: 19.43
+	Hs
		150634 PDLI7_HUMAN (1774-2194): 2.23e-29: 126: 13.48		ABLM1_HUMAN (2-513): 5.92e-34: 140: 11.69
+	Hs
		282330 FHL3_HUMAN (2105-2192): 3.61e-23: 103: 21.59		NEBL_HUMAN (68-653): 1.79e-40: 161: 18.00
+	Hs
		150539 PAXI_HUMAN (279-339): 4.6e-10: 67: 24.59		ABLM1_HUMAN (2-513): 5.92e-34: 140: 11.69
+	Hs
		1044592 FHL3_HUMAN (2105-2192): 3.61e-23: 103: 21.59		LASP1_HUMAN (538-653): 3.97e-23: 101: 35.66
+	Hs
		1044619 FHL3_HUMAN (2105-2192): 3.61e-23: 103: 21.59		CRIP3_HUMAN (5-57): 1.73e-21: 95.4: 29.63
+	Hs
		301014 PDLI7_HUMAN (1774-2194): 2.23e-29: 126: 13.48		ABLM3_HUMAN (5-591): 4.23e-12: 71.3: 8.42
+	Mm
		1113253 PAXI_MOUSE (279-339): 1.68e-09: 65: 24.59		SRBS2_MOUSE (502-654): 9.67e-21: 99.7: 22.88
+	Hs
		816232 LIMS1_HUMAN (2018-2076): 7.83e-12: 71: 33.90		CSRP3_HUMAN (4-101): 1.81e-19: 88.9: 24.17
+	Hs
		823484 PAXI_HUMAN (279-339): 4.6e-10: 67: 24.59		SRBS1_HUMAN (593-653): 4.9e-09: 61.9: 32.79