Interactor 1: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Interactor 2: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 30236477, 12086892, 8631822, 9207067, 22897854, 12207021, 25132001
Identification Methods fluorescent resonance energy transfer, biochemical, x-ray crystallography, comigration in non denaturing gel electrophoresis, cross-linking study, circular dichroism, differential scanning calorimetry, comigration in sds page
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDGF~PDGF
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001541 - ovarian follicle development
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis
and 139 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 395
Hs

1 395
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024