HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 499
+	Hs
		550182 PABP1_HUMAN (1-636): 0: 571: 100.00		CLK3_HUMAN (1-499): 4.5e-133: 395: 59.32
+	Hs
		550125 PABP1_HUMAN (1-636): 0: 571: 100.00		CDK2_HUMAN (160-488): 2.04e-132: 387: 24.70
+	Hs
		889723 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		CLK3_HUMAN (1-499): 4.5e-133: 395: 59.32
+	Hs
		550275 PABP1_HUMAN (1-636): 0: 571: 100.00		DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50
+	Hs
		1101947 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50
+	Hs
		889633 PABP5_HUMAN (103-397): 1.23e-52: 187: 33.22		CLK2_HUMAN (1-499): 6.98e-147: 431: 100.00
+	Hs
		889786 PABP5_HUMAN (103-397): 1.23e-52: 187: 33.22		CLK3_HUMAN (1-499): 4.5e-133: 395: 59.32
+	Hs
		620208 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CLK1_HUMAN (1-484): 2.4e-143: 422: 53.31
+	Hs
		443169 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		CDK1_HUMAN (160-483): 1.01e-113: 339: 24.10
+	Hs
		620353 NUCL_HUMAN (3-89): 4.28e-20: 96.8: 33.33		DYR1A_HUMAN (108-485): 8.54e-105: 331: 28.50