HitPredict

Interactor 1: ZEP1 (P15822)
Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)
Gene: HIVEP1

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	25332235, 28514442, 33961781, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2718 Hs			1 542
+	Hs
		681186 ZEP2_HUMAN (332-2324): 0: 1190: 29.76		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		681187 ZEP2_HUMAN (332-2324): 0: 1190: 29.76		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		550448 ZEP1_HUMAN (2-2718): 0: 801: 100.00		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1163022 ZN764_HUMAN (389-457): 7.59e-11: 68.8: 37.68		TRAF7_HUMAN (353-522): 1.18e-28: 122: 27.17
+	Hs
		1033649 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		TAF5_HUMAN (352-541): 4.24e-21: 99.2: 19.39
+	Hs
		1074813 IKZF3_HUMAN (358-457): 1.52e-11: 71.9: 35.00		TAF5_HUMAN (352-541): 4.24e-21: 99.2: 19.39
+	Hs
		1033680 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		POC1A_HUMAN (145-308): 4.51e-14: 76: 17.26