HitPredict

Interactor 1: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Interactor 2: RFC1 (P38630)
Replication factor C subunit 1 (Replication factor C1) (Activator 1 95 kDa subunit) (Cell division control protein 44)
Gene: RFC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 8995429, 20967232, 25450506, 20455582, 22197374
Identification Methods affinity chromatography technology, two hybrid, pull down, x-ray crystallography, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~PCNA_C, AAA~PCNA_N
Common GO terms GO:0000278 - mitotic cell cycle
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006272 - leading strand elongation
GO:0006298 - mismatch repair
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 258
Sc

1 861
+ Hs
+ Ce
+ Hs
+ Dm
+ Hs
+ Hs
+ Bt
+ Hs
+ Dm
+ Bt
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024