Interactor 1: CHIN (P15882)
N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)
Gene: CHN1

Interactor 2: CHIO (P52757)
Beta-chimaerin (Beta-chimerin) (Rho GTPase-activating protein 3)
Gene: CHN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~SH2, RhoGAP~RhoGAP, SH2~SH2
Common GO terms GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0046872 - metal ion binding
GO:0051056 - regulation of small GTPase mediated signal transduction
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 459
Hs

1 468
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Last updated: 15 Jul 2024