HitPredict

Interactor 1: ITF2 (P15884)
Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: TCF4

Interactor 2: MTG8 (Q06455)
Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)
Gene: RUNX1T1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	25609649, 28514442, 33961781, 37207277
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 604
+	Hs
		987459 HTF4_HUMAN (3-667): 0: 783: 61.71		MTG8_HUMAN (1-604): 0: 935: 100.00
+	Mm
		222897 ITF2_MOUSE (1-667): 0: 918: 96.87		MTG16_MOUSE (31-604): 0: 779: 69.98
+	Hs
		203437 ITF2_HUMAN (1-667): 0: 908: 100.00		MTG8R_HUMAN (32-591): 0: 778: 64.77
+	Hs
		253964 ITF2_HUMAN (1-667): 0: 908: 100.00		MTG16_HUMAN (30-604): 0: 772: 69.18
+	Hs
		551510 TFE2_HUMAN (1-667): 0: 733: 49.71		MTG8_HUMAN (1-604): 0: 935: 100.00
+	Hs
		254000 HTF4_HUMAN (3-667): 0: 783: 61.71		MTG16_HUMAN (30-604): 0: 772: 69.18
+	Mm
		222898 HTF4_MOUSE (3-667): 0: 771: 59.22		MTG16_MOUSE (31-604): 0: 779: 69.98
+	Hs
		253965 TFE2_HUMAN (1-667): 0: 733: 49.71		MTG16_HUMAN (30-604): 0: 772: 69.18
+	Mm
		222892 TFE2_MOUSE (1-667): 0: 702: 47.69		MTG16_MOUSE (31-604): 0: 779: 69.98