Protein: XIRP2
Xin actin-binding repeat-containing protein 2 (Beta-xin) (Cardiomyopathy-associated protein 3) (Xeplin)

Gene: XIRP2
Organism: Homo sapiens
Interactions: 43
UniProt ID: A4UGR9

Gene Ontology (top 5):
GO:0003281 - ventricular septum development
GO:0005911 - cell-cell junction
GO:0007015 - actin filament organization
GO:0030018 - Z disc
GO:0045216 - cell-cell junction organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62744

NEBL
Nebulette

1

3

Small-scale

0.607

High

62755

NEBU
Nebulin

1

3

Small-scale

0.586

High

62747

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.513

High

62767

FLNC
Filamin-C

1

1

Small-scale

0.501

High

62780

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.489

High

62781

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.489

High

62751

H14
Histone H1.4

1

1

High-throughput

0.470

High

62754

H15
Histone H1.5

1

1

High-throughput

0.470

High

62774

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

62759

VASP
Vasodilator-stimulated phosphoprotein

1

3

High-throughput

0.457

High

62761

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.437

High

62762

H31
Histone H3.1

1

1

High-throughput

0.437

High

62772

H32
Histone H3.2

1

1

High-throughput

0.437

High

62743

DYSF
Dysferlin

1

0

High-throughput

0.282

High

62770

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

Small-scale

0.279

Low

62746

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.279

Low

62766

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.279

Low

62768

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

0

High-throughput

0.279

Low

62777

FAN
Protein FAN

1

0

High-throughput

0.279

Low

62783

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.279

Low

62757

TTK
Dual specificity protein kinase TTK

1

0

High-throughput

0.269

Low

62775

PNPT1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial

1

0

High-throughput

0.269

Low

62778

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.269

Low

62742

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.249

Low

62745

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.249

Low

62748

LATS1
Serine/threonine-protein kinase LATS1

1

0

High-throughput

0.249

Low

62749

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low

62750

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.249

Low

62752

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.249

Low

62753

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

62756

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

62758

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

62760

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

62763

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

62764

PABP4
Polyadenylate-binding protein 4

1

0

High-throughput

0.249

Low

62765

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

62771

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

62773

RTKN2
Rhotekin-2

1

0

High-throughput

0.249

Low

62776

LRC8C
Volume-regulated anion channel subunit LRRC8C

1

0

High-throughput

0.249

Low

62779

BT3L4
Transcription factor BTF3 homolog 4

1

0

High-throughput

0.249

Low

62782

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

62784

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low

62769

CRY1
Cryptochrome-1

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025