HitPredict

Interactor 1: ABP1 (P15891)
Actin-binding protein
Gene: ABP1

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	11331312, 11805837, 30042427, 37797614, 16429126
Identification Methods	biochemical, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Actin~Cofilin_ADF
Common GO terms	GO:0005884 - actin filament GO:0030479 - actin cortical patch
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Sc			1 375
+	Hs
		1084964 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTBL_HUMAN (2-375): 0: 687: 83.42
+	Hs
		282322 NEBL_HUMAN (9-592): 3.79e-62: 223: 13.70		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		891799 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		929879 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		596202 NEBU_HUMAN (64-591): 6.24e-45: 174: 15.20		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		932187 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		930053 PACN2_HUMAN (131-591): 1.56e-44: 167: 15.48		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		915391 DREB_HUMAN (3-560): 2.74e-47: 177: 11.55		ACTA_HUMAN (2-375): 0: 589: 86.63
+	Hs
		596210 NEBU_HUMAN (64-591): 6.24e-45: 174: 15.20		ACTH_HUMAN (2-375): 0: 587: 86.63
+	Ce
		501469 Q9XUT0_CAEEL (6-591): 8.49e-38: 150: 17.56		ACT2_CAEEL (2-375): 0: 598: 89.04
+	Hs
		891757 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		929858 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		891762 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		929863 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		891770 LASP1_HUMAN (364-591): 7.05e-30: 120: 19.74		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		932976 COTL1_HUMAN (6-148): 2.23e-33: 126: 17.24		ACTS_HUMAN (2-375): 0: 590: 86.90
+	Hs
		932154 SRC8_HUMAN (318-590): 3.04e-29: 124: 21.63		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Mm
		892211 COTL1_MOUSE (6-148): 5.63e-29: 113: 16.55		ACTB_MOUSE (1-375): 0: 601: 88.80
+	Mm
		929806 COTL1_MOUSE (6-148): 5.63e-29: 113: 16.55		ACTG_MOUSE (1-375): 0: 600: 89.07
+	Mm
		915552 LASP1_MOUSE (364-591): 2.21e-29: 119: 20.61		ACTA_MOUSE (2-375): 0: 589: 86.63