HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: RAG2 (P55895)
V(D)J recombination-activating protein 2 (RAG-2)
Gene: RAG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 26124138, 9036966, 9630231, 8777717, 14670978, 25745109
Identification Methods biochemical, affinity chromatography technology, pull down
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RAG1~RAG2
Common GO terms GO:0002331 - pre-B cell allelic exclusion
GO:0005654 - nucleoplasm
GO:0006325 - chromatin organization
GO:0008270 - zinc ion binding
GO:0030183 - B cell differentiation
and 5 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1043
Hs

1 527
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024