Interactor 1: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1
Interactor 2: FANCJ (Q9BX63)
Fanconi anemia group J protein (EC 3.6.4.12) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)
Gene: BRIP1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.771 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27399284, 23530059, 24573678, 15242590, 17525340, 17664283, 16391231, 18628483, 28911102, 34591612, 21240188, 20173781, 17581638, 17596542, 22032289, 25184681, 23157317, 26831064, 11877378, 14576433 and 18 others
more... |
| Identification Methods | affinity chromatography technology, unspecified method, pull down, x-ray crystallography, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, tandem affinity purification, isothermal titration calorimetry, surface plasmon resonance and 1 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006281 - DNA repair and 4 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
