HitPredict

Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: MARE1 (Q15691)
Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1)
Gene: MAPRE1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	25225338
Identification Methods	pull down, reverse ras recruitment system, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 2871 Hs			1 268
+	Hs
		1077108 CP250_HUMAN (1093-2582): 3.26e-49: 197: 10.07		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		828641 CENPF_HUMAN (11-1800): 6.64e-55: 215: 10.64		MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70
+	Hs
		1068538 PLEC_HUMAN (20-1265): 9.18e-42: 172: 9.33		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		969589 CENPE_HUMAN (1293-2534): 2.34e-36: 154: 10.36		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		1045422 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		1077099 AKAP9_HUMAN (1336-2427): 2.28e-27: 125: 8.91		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		974082 DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		1045564 SPTN1_HUMAN (235-2163): 6.27e-28: 126: 9.67		MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70
+	Hs
		1307592 AKAP9_HUMAN (1336-2427): 2.28e-27: 125: 8.91		MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70
+	Hs
		166713 CE290_HUMAN (30-867): 9.79e-15: 83.5: 8.20		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		974173 DYST_HUMAN (91-2218): 3.51e-25: 118: 10.10		MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70
+	Mm
		1142238 MACF1_MOUSE (1987-2820): 1.6e-10: 69.5: 12.38		MARE1_MOUSE (1-257): 1.2e-149: 420: 96.89
+	Hs
		1077170 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Hs
		963333 SPTB2_HUMAN (1169-2330): 8.03e-10: 67.2: 8.93		MARE1_HUMAN (1-257): 3.32e-150: 421: 100.00
+	Dm
		54305 A1Z9J2_DROME (187-1375): 2.35e-19: 98.7: 10.66		Q9XZ57_DROME (1-265): 4e-126: 361: 52.60
+	Hs
		1357665 MACF1_HUMAN (1987-2820): 9.45e-10: 67.2: 12.38		MARE3_HUMAN (1-268): 1.91e-134: 382: 63.70