HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: MP2K2 (P36507)
Dual specificity mitogen-activated protein kinase kinase 2 (MAP kinase kinase 2) (MAPKK 2) (EC 2.7.12.2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK 2)
Gene: MAP2K2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 400
+	Hs
		552533 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MP2K1_HUMAN (2-399): 2.32e-128: 376: 78.14
+	Hs
		552039 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		AKT2_HUMAN (31-365): 1.76e-125: 372: 20.95
+	Hs
		552038 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		AKT1_HUMAN (43-351): 3.37e-124: 369: 20.12
+	Hs
		551975 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CDK2_HUMAN (69-375): 3.95e-124: 362: 25.16
+	Hs
		551896 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KAPCA_HUMAN (32-347): 6.67e-122: 358: 22.99
+	Hs
		414714 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CDK1_HUMAN (69-375): 8.1e-111: 328: 24.76
+	Hs
		554187 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		STK24_HUMAN (52-388): 2.56e-104: 317: 29.83
+	Hs
		553937 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		STK26_HUMAN (69-388): 2.38e-104: 316: 30.12
+	Hs
		552801 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KS6A1_HUMAN (1-347): 1.75e-92: 295: 19.33
+	Hs
		414898 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		CDK1_HUMAN (69-375): 8.1e-111: 328: 24.76