HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: BRD2 (P25440)
Bromodomain-containing protein 2 (O27.1.1)
Gene: BRD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0007283 - spermatogenesis GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 801
+	Hs
		631492 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		391554 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD2_HUMAN (1-773): 1.09e-171: 517: 100.00
+	Hs
		555470 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		1067038 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD3_HUMAN (53-764): 4.91e-124: 390: 56.56
+	Hs
		244848 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		244634 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		244795 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		243783 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BRD4_HUMAN (26-765): 9.66e-99: 336: 45.89
+	Hs
		555430 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		998866 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		391671 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		EP300_HUMAN (31-183): 5.52e-39: 159: 30.72
+	Hs
		555570 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2B_HUMAN (293-452): 1.59e-31: 134: 25.00
+	Hs
		555569 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38
+	Hs
		319113 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BRD1_HUMAN (54-330): 3.85e-29: 127: 17.79
+	Hs
		391824 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		KAT2A_HUMAN (293-452): 5.67e-30: 129: 24.38
+	Hs
		1300654 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13
+	Hs
		555661 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ1A_HUMAN (49-197): 1.07e-22: 106: 21.94
+	Hs
		1296215 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		BRD7_HUMAN (25-338): 4.42e-29: 125: 17.13
+	Hs
		555528 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33
+	Hs
		391768 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PB1_HUMAN (306-773): 2.79e-18: 92.6: 12.33