HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	20000738
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019899 - enzyme binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 246
+	Hs
		555389 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		555406 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		391567 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		470333 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		555302 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		391557 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		470276 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82