HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: LAR1B (Q659C4)
La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2)
Gene: LARP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 914
+	Hs
		470423 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		470428 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		LARP4_HUMAN (114-703): 1.5e-97: 323: 13.29
+	Hs
		403075 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		555492 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116472 H2A1A_HUMAN (1-125): 8.26e-67: 200: 92.00		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116493 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116374 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116433 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116457 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116320 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116351 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		391731 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		470408 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		594850 H2A1D_HUMAN (1-129): 1.02e-65: 197: 90.70		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1087010 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Hs
		1116511 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		LARP7_HUMAN (215-521): 2.19e-40: 159: 16.72
+	Sc
		392372 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		LHP1_YEAST (212-447): 8.47e-35: 136: 15.20