HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: ZMYD8 (Q9ULU4)
MYND-type zinc finger-containing chromatin reader ZMYND8 (Cutaneous T-cell lymphoma-associated antigen se14-3) (CTCL-associated antigen se14-3) (Protein kinase C-binding protein 1) (Rack7) (Transcription coregulator ZMYND8) (Zinc finger MYND domain-containing protein 8)
Gene: ZMYND8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0090734 - site of DNA damage
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 1186
+	Hs
		391965 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		ZMYD8_HUMAN (1-1186): 0: 1251: 100.00
+	Hs
		331860 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		331703 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		331824 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		NSD2_HUMAN (17-359): 5.44e-55: 212: 17.31
+	Hs
		170185 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		TIF1A_HUMAN (38-288): 2.75e-50: 196: 24.44
+	Hs
		1087066 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		PHIP_HUMAN (152-648): 3.22e-48: 191: 14.68
+	Hs
		555681 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ2A_HUMAN (82-251): 2.51e-37: 155: 18.50
+	Hs
		555661 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		555434 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		BPTF_HUMAN (57-256): 6.93e-34: 144: 19.81
+	Hs
		391923 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		BAZ1A_HUMAN (5-252): 1.74e-36: 152: 14.63
+	Hs
		555528 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		555569 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		555570 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93
+	Hs
		391768 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Hs
		1087035 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		PB1_HUMAN (115-379): 7.74e-19: 95.1: 11.57
+	Mm
		1151749 H2A2A_MOUSE (1-129): 7e-66: 197: 91.47		KAT2B_MOUSE (142-251): 4.13e-14: 79.2: 28.83
+	Hs
		391824 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		391825 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93
+	Hs
		1087072 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		KAT2A_HUMAN (142-251): 1.37e-13: 77.6: 27.03
+	Hs
		1087073 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		KAT2B_HUMAN (142-251): 2.88e-13: 76.5: 27.93