Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 9677323, 15767546, 7682895, 28205554, 7523122, 7535778, 11046132
Identification Methods enzymatic study, fluorescent resonance energy transfer, affinity chromatography technology, far western blotting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001553 - luteinization
GO:0001701 - in utero embryonic development
GO:0001775 - cell activation
GO:0002244 - hematopoietic progenitor cell differentiation
GO:0004672 - protein kinase activity
and 59 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1089
Hs

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Last updated: 15 Jul 2024