HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 326
+	Hs
		559339 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		488920 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		717721 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		559322 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		RO52_HUMAN (5-198): 5.75e-52: 180: 18.78
+	Hs
		559475 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		559905 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		489219 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		282516 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00