HitPredict

Interactor 1: ODPX (P16451)
Pyruvate dehydrogenase complex protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (Pyruvate dehydrogenase complex component E3BP)
Gene: PDX1

Interactor 2: PREP (P32898)
Presequence protease, mitochondrial (PreP) (EC 3.4.24.-) (Metalloprotease of 112 kDa) (Pitrilysin metalloproteinase) (Protease M)
Gene: CYM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 410 Sc			1 989
+	Sc
		520808 ODP2_YEAST (5-393): 2.98e-87: 274: 20.82		PREP_YEAST (1-989): 0: 806: 100.00
+	Hs
		126205 ODPX_HUMAN (13-381): 8.51e-88: 277: 19.36		MPPB_HUMAN (3-487): 1.08e-117: 371: 13.07
+	Hs
		264821 ODB2_HUMAN (15-387): 2.21e-88: 277: 14.46		MPPB_HUMAN (3-487): 1.08e-117: 371: 13.07
+	Hs
		126241 ODPX_HUMAN (13-381): 8.51e-88: 277: 19.36		MPPA_HUMAN (4-488): 1.77e-109: 351: 10.06
+	Hs
		505967 ODB2_HUMAN (15-387): 2.21e-88: 277: 14.46		MPPA_HUMAN (4-488): 1.77e-109: 351: 10.06
+	Hs
		264818 ODP2_HUMAN (3-158): 2e-32: 131: 26.28		MPPB_HUMAN (3-487): 1.08e-117: 371: 13.07
+	Hs
		489735 ODP2_HUMAN (3-158): 2e-32: 131: 26.28		MPPA_HUMAN (4-488): 1.77e-109: 351: 10.06
+	Hs
		264859 ODO2_HUMAN (34-104): 2.77e-11: 66.8: 29.58		MPPB_HUMAN (3-487): 1.08e-117: 371: 13.07
+	Hs
		739089 ODO2_HUMAN (34-104): 2.77e-11: 66.8: 29.58		MPPA_HUMAN (4-488): 1.77e-109: 351: 10.06