HitPredict

Interactor 1: BIP (P16474)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78) (Immunoglobulin heavy chain-binding protein homolog) (BiP)
Gene: KAR2

Interactor 2: JEM1 (P40358)
DnaJ-like chaperone JEM1 (DnaJ-like protein of the ER membrane 1)
Gene: JEM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.812

The method score is based on:

Property Details
Experiments 18754794, 20430885
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~HSP70
Common GO terms GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0036503 - ERAD pathway
GO:0051082 - unfolded protein binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024