Protein: SEPT6
Septin-6

Gene: SEPT6, SEPTIN6
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q14141

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000776 - kinetochore
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1048992

SEPT2
Septin-2

12

19

Small-scale

0.983

High

1049019

SEPT9
Septin-9

10

19

Small-scale

0.977

High

1048996

SEPT7
Septin-7

10

19

Small-scale

0.975

High

1049010

SEPT5
Septin-5

7

19

Small-scale

0.973

High

1049005

SEPT1
Septin-1

7

19

High-throughput

0.971

High

1049001

SEP12
Septin-12

6

19

Small-scale

0.950

High

1049018

SEPT3
Neuronal-specific septin-3

5

19

High-throughput

0.931

High

1049016

SEP10
Septin-10

5

19

High-throughput

0.919

High

1049006

SEPT8
Septin-8

4

20

High-throughput

0.903

High

1049015

SEP11
Septin-11

4

19

High-throughput

0.903

High

198190

SEPT4
Septin-4

3

20

High-throughput

0.861

High

1048999

SEP14
Septin-14

3

19

High-throughput

0.861

High

1049012

BORG4
Cdc42 effector protein 4

3

15

High-throughput

0.667

High

496998

TAU
Microtubule-associated protein tau

2

15

High-throughput

0.628

High

1049002

MORN4
MORN repeat-containing protein 4

3

2

High-throughput

0.616

High

1049014

ANLN
Anillin

2

11

High-throughput

0.611

High

854097

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

3

2

High-throughput

0.609

High

1023273

TRI32
E3 ubiquitin-protein ligase TRIM32

3

3

High-throughput

0.609

High

3376

A0A0S2Z5W9
Septin 9 isoform 3

1

20

High-throughput

0.590

High

350164

RASK
GTPase KRas

2

19

High-throughput

0.584

High

856676

RM12
Large ribosomal subunit protein bL12m

2

9

High-throughput

0.574

High

1049008

SH3K1
SH3 domain-containing kinase-binding protein 1

2

7

Small-scale

0.543

High

502089

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.536

High

802595

CRK
Adapter molecule crk

2

8

High-throughput

0.526

High

1049013

PKHF2
Pleckstrin homology domain-containing family F member 2

1

5

High-throughput

0.523

High

377318

GCR
Glucocorticoid receptor

1

12

High-throughput

0.515

High

1049007

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.515

High

146675

SOCS7
Suppressor of cytokine signaling 7

1

2

Small-scale

0.506

High

150125

BORG1
Cdc42 effector protein 2

1

15

Small-scale

0.501

High

1049000

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.501

High

674420

UFO
Tyrosine-protein kinase receptor UFO

1

20

High-throughput

0.500

High

120917

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.493

High

602837

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

High-throughput

0.493

High

453352

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

Small-scale

0.489

High

725434

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.489

High

1049009

ACAP3
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3

1

10

High-throughput

0.489

High

162731

XPO1
Exportin-1

1

12

High-throughput

0.479

High

198259

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

2

High-throughput

0.479

High

348661

RASN
GTPase NRas

1

19

High-throughput

0.479

High

349316

RASH
GTPase HRas

1

17

High-throughput

0.479

High

507014

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

842341

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

893995

CDC42
Cell division control protein 42 homolog

1

10

High-throughput

0.479

High

1048990

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.479

High

566387

KPCA
Protein kinase C alpha type

1

1

High-throughput

0.470

High

791553

HD
Huntingtin

1

8

High-throughput

0.470

High

904548

1433G
14-3-3 protein gamma

1

1

High-throughput

0.470

High

1048993

SETB1
Histone-lysine N-methyltransferase SETDB1

1

4

High-throughput

0.470

High

1049011

NSD3
Histone-lysine N-methyltransferase NSD3

1

5

High-throughput

0.464

High

1048991

CUL7
Cullin-7

1

0

High-throughput

0.458

High

1049020

BORG2
Cdc42 effector protein 3

1

15

Small-scale

0.457

High

227420

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.437

High

329713

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

338417

EGFR
Epidermal growth factor receptor

1

17

High-throughput

0.437

High

383800

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

19

High-throughput

0.437

High

435638

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.437

High

452422

PGFRB
Platelet-derived growth factor receptor beta

1

18

High-throughput

0.437

High

507993

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.437

High

529097

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.437

High

547048

EZRI
Ezrin

1

3

High-throughput

0.437

High

607965

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

651173

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

665599

EPHB2
Ephrin type-B receptor 2

1

14

High-throughput

0.437

High

720433

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

786344

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

High-throughput

0.437

High

872441

EPHA5
Ephrin type-A receptor 5

1

16

High-throughput

0.437

High

959413

VIGLN
Vigilin

1

1

High-throughput

0.437

High

998692

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.437

High

1048994

EPHA7
Ephrin type-A receptor 7

1

11

High-throughput

0.437

High

1048995

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

1048997

VIR
Protein virilizer homolog

1

4

High-throughput

0.437

High

1048998

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1049004

BICD2
Protein bicaudal D homolog 2

1

7

High-throughput

0.437

High

1049017

CEP72
Centrosomal protein of 72 kDa

1

1

High-throughput

0.437

High

1049021

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

239989

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.407

High

787231

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.407

High

831315

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.373

High

949016

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

281621

WFS1
Wolframin

1

0

High-throughput

0.268

Low

602524

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.268

Low

660487

GRN
Progranulin

1

0

High-throughput

0.268

Low

1049003

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low

232160

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.265

Low

378689

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

127786

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.249

Low

414624

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

High-throughput

0.249

Low

575431

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024