HitPredict

Interactor 1: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Interactor 2: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001701 - in utero embryonic development GO:0005634 - nucleus GO:0005829 - cytosol GO:0010468 - regulation of gene expression
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 326
+	Hs
		717672 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00
+	Hs
		563182 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		931357 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		1304114 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		RING2_HUMAN (7-227): 8.37e-50: 170: 16.61
+	Hs
		282612 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00