HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: EFNB1 (P98172)
Ephrin-B1 (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF); Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Gene: EFNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045121 - membrane raft GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 346
+	Hs
		957933 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		950924 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		925193 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		893900 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		900377 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		545322 RAC2_HUMAN (10-196): 1.67e-76: 229: 62.03		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		892317 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		915606 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		436254 RHOC_HUMAN (1-192): 1.16e-74: 225: 50.52		EFNB1_HUMAN (1-346): 0: 538: 100.00
+	Hs
		856571 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		564458 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856523 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856515 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856517 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856514 RAC3_HUMAN (10-183): 9.1e-76: 227: 66.67		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856522 RHOB_HUMAN (1-204): 1.77e-75: 227: 49.51		EFNB2_HUMAN (8-346): 1.88e-155: 441: 55.39
+	Hs
		856359 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EFNA4_HUMAN (13-211): 5.6e-53: 175: 23.42