Protein: MARH1
E3 ubiquitin-protein ligase MARCHF1 (EC 2.3.2.27) (Membrane-associated RING finger protein 1) (Membrane-associated RING-CH protein I) (MARCH-I) (RING finger protein 171) (RING-type E3 ubiquitin transferase MARCHF1)

Gene: MARH1, MARCHF1
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q8TCQ1

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0002495 - antigen processing and presentation of peptide antigen via MHC class II
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

439796

INSR
Insulin receptor

2

2

Small-scale

0.624

High

380323

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

1

Small-scale

0.595

High

125771

STXB3
Syntaxin-binding protein 3

1

1

High-throughput

0.536

High

163329

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

6

High-throughput

0.536

High

226145

STX6
Syntaxin-6

1

6

High-throughput

0.536

High

249881

STX10
Syntaxin-10

1

6

High-throughput

0.536

High

331903

GOSR1
Golgi SNAP receptor complex member 1

1

1

High-throughput

0.536

High

467283

MDR1
ATP-dependent translocase ABCB1

1

2

High-throughput

0.536

High

472099

MET
Hepatocyte growth factor receptor

1

4

High-throughput

0.536

High

522702

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

7

High-throughput

0.536

High

614712

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

7

High-throughput

0.536

High

641217

FGFR2
Fibroblast growth factor receptor 2

1

3

High-throughput

0.536

High

648599

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.536

High

658739

JAK1
Tyrosine-protein kinase JAK1

1

3

High-throughput

0.536

High

690109

AVR2A
Activin receptor type-2A

1

8

High-throughput

0.536

High

710644

EPHA3
Ephrin type-A receptor 3

1

3

High-throughput

0.536

High

787211

BMR1A
Bone morphogenetic protein receptor type-1A

1

8

High-throughput

0.536

High

788971

TGFR2
TGF-beta receptor type-2

1

8

High-throughput

0.536

High

857510

NOTC1
Neurogenic locus notch homolog protein 1

1

5

High-throughput

0.536

High

931971

EPHB4
Ephrin type-B receptor 4

1

2

High-throughput

0.536

High

933448

S12A2
Solute carrier family 12 member 2

1

4

High-throughput

0.536

High

963446

STXB1
Syntaxin-binding protein 1

1

1

High-throughput

0.536

High

1047653

NOTC2
Neurogenic locus notch homolog protein 2

1

5

High-throughput

0.536

High

1102731

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

7

High-throughput

0.536

High

1118380

BMPR2
Bone morphogenetic protein receptor type-2

1

8

High-throughput

0.536

High

1278294

LRP10
Low-density lipoprotein receptor-related protein 10

1

3

High-throughput

0.536

High

1334476

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.536

High

1349892

PAQR1
Adiponectin receptor protein 1

1

2

High-throughput

0.536

High

1349895

REEP6
Receptor expression-enhancing protein 6

1

1

High-throughput

0.536

High

1349896

SNX27
Sorting nexin-27

1

3

High-throughput

0.536

High

1349897

NFIP1
NEDD4 family-interacting protein 1

1

1

High-throughput

0.536

High

1349898

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

3

High-throughput

0.536

High

1349899

AGRL3
Adhesion G protein-coupled receptor L3

1

1

High-throughput

0.536

High

1349900

CD320
CD320 antigen

1

1

High-throughput

0.536

High

1349902

NFIP2
NEDD4 family-interacting protein 2

1

1

High-throughput

0.536

High

1349906

ZNRF3
E3 ubiquitin-protein ligase ZNRF3

1

2

High-throughput

0.536

High

1349907

NOTC3
Neurogenic locus notch homolog protein 3

1

5

High-throughput

0.536

High

1349908

S12A4
Solute carrier family 12 member 4

1

4

High-throughput

0.536

High

249639

SNX3
Sorting nexin-3

1

0

High-throughput

0.513

High

582184

INGR1
Interferon gamma receptor 1

1

0

High-throughput

0.513

High

828230

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.513

High

846769

GRK6
G protein-coupled receptor kinase 6

1

0

High-throughput

0.513

High

895360

S26A2
Sulfate transporter

1

0

High-throughput

0.513

High

935690

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.513

High

1309854

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.513

High

1349911

KC1G3
Casein kinase I isoform gamma-3

1

0

High-throughput

0.513

High

508319

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

9

Small-scale

0.501

High

883288

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

19

Small-scale

0.501

High

906714

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.501

High

970817

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

Small-scale

0.501

High

127707

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

6

Small-scale

0.479

High

390689

TFR1
Transferrin receptor protein 1

1

2

Small-scale

0.479

High

717914

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.479

High

718152

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

Small-scale

0.479

High

837297

CD86
T-lymphocyte activation antigen CD86

1

5

Small-scale

0.479

High

1125564

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

1256831

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

1

Small-scale

0.479

High

1292845

STING
Stimulator of interferon genes protein

1

1

Small-scale

0.479

High

1349901

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

1349903

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

2

High-throughput

0.479

High

1349904

OCAD1
OCIA domain-containing protein 1

1

2

High-throughput

0.479

High

1349905

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

3

High-throughput

0.479

High

1349894

HDA11
Histone deacetylase 11

1

0

Small-scale

0.458

High

1278041

MAVS
Mitochondrial antiviral-signaling protein

1

2

Small-scale

0.437

High

1312195

MIRO2
Mitochondrial Rho GTPase 2

1

3

High-throughput

0.437

High

1349893

S2546
Mitochondrial outer membrane protein SLC25A46

1

2

High-throughput

0.437

High

1349910

MTCH2
Mitochondrial carrier homolog 2

1

5

High-throughput

0.437

High

1349909

VP9D1
VPS9 domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025