HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: BMPR2 (Q13873)
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
Gene: BMPR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1038
+	Hs
		1046386 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		BMPR2_HUMAN (1-1038): 0: 868: 100.00
+	Hs
		950982 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		BMPR2_HUMAN (1-1038): 0: 868: 100.00
+	Hs
		925266 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		BMPR2_HUMAN (1-1038): 0: 868: 100.00
+	Hs
		893991 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BMPR2_HUMAN (1-1038): 0: 868: 100.00
+	Mm
		1143794 RHOJ_MOUSE (9-185): 3.89e-105: 303: 83.05		TGFR2_MOUSE (8-504): 1.23e-137: 427: 30.19
+	Hs
		738409 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75
+	Hs
		738577 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Mm
		983317 RAC2_MOUSE (10-196): 9.47e-77: 230: 61.50		TGFR2_MOUSE (8-504): 1.23e-137: 427: 30.19
+	Mm
		1142495 RHOJ_MOUSE (9-185): 3.89e-105: 303: 83.05		ACVL1_MOUSE (49-512): 9.74e-107: 344: 29.80
+	Hs
		738321 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75
+	Hs
		738322 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		BMR1A_HUMAN (51-510): 1.95e-132: 412: 28.75
+	Hs
		738490 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		ACV1B_HUMAN (59-512): 3.73e-101: 329: 29.07
+	Hs
		564416 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		AVR2A_HUMAN (11-515): 1.01e-122: 386: 32.49
+	Hs
		739935 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		TGFR2_HUMAN (8-521): 1.09e-118: 378: 29.66
+	Hs
		564434 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Hs
		738527 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Hs
		738521 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Hs
		738516 CDC42_HUMAN (9-193): 1.09e-78: 235: 67.57		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Hs
		738517 RHOA_HUMAN (1-201): 1.3e-76: 230: 49.75		TGFR1_HUMAN (59-504): 1.1e-110: 354: 29.30
+	Mm
		983316 RAC2_MOUSE (10-196): 9.47e-77: 230: 61.50		ACVL1_MOUSE (49-512): 9.74e-107: 344: 29.80