HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: PHO80 (P20052)
PHO85 cyclin PHO80 (Aminoglycoside antibiotic sensitivity protein 3) (Phosphate system cyclin PHO80)
Gene: PHO80

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 7939631, 11069666, 28637746, 37968396, 20489023, 8108735, 7565699, 16429126, 18042456, 18719252, 15057567, 24876385
Identification Methods coimmunoprecipitation, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, enzymatic study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin~Pkinase
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016242 - negative regulation of macroautophagy
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 305
Sc

1 293
+ At
+ At
+ At
+ At
+ At
+ At
+ Sc
+ Sc
+ Hs
+ At
+ At
+ Hs
+ At
+ Sc
+ Sc
+ Sp
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024