HitPredict

Interactor 1: PHO85 (P17157)
Cyclin-dependent protein kinase PHO85 (EC 2.7.11.22) (Negative regulator of the PHO system) (Serine/threonine-protein kinase PHO85)
Gene: PHO85

Interactor 2: PRR1 (P28708)
Serine/threonine-protein kinase PRR1 (EC 2.7.11.1) (Pheromone response regulator 1)
Gene: PRR1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 20489023, 16319894
Identification Methods affinity chromatography technology, enzymatic study, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 2 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 305
Sc

1 518
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024