Interactor 1: VATA (P17255)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (Vacuolar proton pump subunit A) [Cleaved into: Endonuclease PI-SceI (EC 3.1.-.-) (Sce VMA intein) (VMA1-derived endonuclease) (VDE)]
Gene: VMA1

Interactor 2: VPP1 (P32563)
V-type proton ATPase subunit a, vacuolar isoform (V-ATPase a 1 subunit) (V-ATPase 95 kDa subunit) (Vacuolar pH protein 1) (Vacuolar proton pump a subunit) (Vacuolar proton translocating ATPase subunit a 1)
Gene: VPH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 11592965, 19081055, 23142977, 25546637, 10747882, 16429126, 33064727, 19473972, 11717306, 28604780, 30910982, 37968396
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0007035 - vacuolar acidification
GO:0016471 - vacuolar proton-transporting V-type ATPase complex
GO:0046961 - proton-transporting ATPase activity, rotational mechanism
GO:1902600 - proton transmembrane transport
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1071
Sc

1 840
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024