HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: CEAM6 (P40199)
Cell adhesion molecule CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) (CEA cell adhesion molecule 6) (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Gene: CEACAM6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	39468006
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Thioredoxin~V-set
Common GO terms	GO:0005615 - extracellular space GO:0009986 - cell surface
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 645 Hs			1 344
+	Hs
		820684 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00
+	Hs
		452190 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00
+	Hs
		717387 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00
+	Hs
		820691 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00
+	Hs
		820645 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00
+	Hs
		452418 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		NTRI_HUMAN (13-314): 2.32e-60: 198: 17.28
+	Hs
		452269 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		MYLK_HUMAN (2-129): 6.12e-12: 69.1: 13.08
+	Hs
		1153007 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		MYLK_HUMAN (2-129): 6.12e-12: 69.1: 13.08
+	Hs
		1142276 PDIA6_HUMAN (522-642): 7.36e-29: 121: 28.10		MYLK_HUMAN (2-129): 6.12e-12: 69.1: 13.08
+	Hs
		717559 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		TITIN_HUMAN (12-341): 2.84e-09: 60.7: 9.54