HitPredict

Interactor 1: ITA2 (P17301)
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)
Gene: ITGA2

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0007160 - cell-matrix adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1181 Hs			1 193
+	Hs
		566873 ITA2_HUMAN (1-1181): 0: 1250: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		566875 ITA2_HUMAN (1-1181): 0: 1250: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		566865 ITA2_HUMAN (1-1181): 0: 1250: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		566872 ITA2_HUMAN (1-1181): 0: 1250: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120298 ITA2_HUMAN (1-1181): 0: 1250: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		880209 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		880211 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436228 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		880212 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		880208 ITA1_HUMAN (1-1169): 0: 1134: 38.84		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545290 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		880207 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		880210 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120368 ITA1_HUMAN (1-1169): 0: 1134: 38.84		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		639881 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		639878 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		639880 ITA3_HUMAN (2-512): 5.18e-65: 241: 18.32		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		436159 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		545210 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		120305 ITA6_HUMAN (14-508): 5.76e-60: 226: 16.10		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98