HitPredict

Interactor 1: CXA1 (P17302)
Gap junction alpha-1 protein (Connexin-43) (Cx43) (Gap junction 43 kDa heart protein)
Gene: GJA1

Interactor 2: STXB1 (P61764)
Syntaxin-binding protein 1 (MUNC18-1) (N-Sec1) (Protein unc-18 homolog 1) (Unc18-1) (Protein unc-18 homolog A) (Unc-18A) (p67)
Gene: STXBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 594
+	Hs
		567075 CXA1_HUMAN (1-382): 0: 545: 100.00		STXB2_HUMAN (1-593): 0: 658: 63.47
+	Hs
		816567 CXA8_HUMAN (1-382): 1.55e-135: 395: 37.81		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Hs
		567195 CXA1_HUMAN (1-382): 0: 545: 100.00		SCFD1_HUMAN (4-588): 8.01e-163: 481: 14.62
+	Hs
		901821 CXD4_HUMAN (6-379): 5.6e-114: 338: 26.39		STXB1_HUMAN (1-594): 0: 680: 100.00
+	Hs
		567291 CXA1_HUMAN (1-382): 0: 545: 100.00		VPS45_HUMAN (12-582): 5.03e-154: 456: 17.81
+	Hs
		1079212 CXD4_HUMAN (6-379): 5.6e-114: 338: 26.39		STXB2_HUMAN (1-593): 0: 658: 63.47
+	Hs
		119662 CXD4_HUMAN (6-379): 5.6e-114: 338: 26.39		STXB3_HUMAN (1-593): 0: 584: 50.59
+	Hs
		1230302 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		SCFD1_HUMAN (4-588): 8.01e-163: 481: 14.62
+	Hs
		1230395 CXD3_HUMAN (1-253): 8.84e-96: 289: 34.39		VPS45_HUMAN (12-582): 5.03e-154: 456: 17.81