Interactor 1: KAPCA (P17612)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001707 - mesoderm formation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 351
Hs

1 425
+ Hs
+ Mm
+ Rn
+ Rn
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024