Protein: GYS1
Glycogen [starch] synthase isoform 1 (EC 2.4.1.11)

Gene: GYS1, GSY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P23337

Gene Ontology (top 5):
GO:0004373 - alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005978 - glycogen biosynthetic process
GO:0042587 - glycogen granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

657171

GYS2
Glycogen [starch] synthase isoform 2

6

3

Small-scale

0.939

High

657191

GLG2
Glycogenin-2

3

8

High-throughput

0.860

High

657169

GYS1
Glycogen [starch] synthase isoform 1

3

3

High-throughput

0.814

High

657182

GLG1
Glycogenin-1

2

8

High-throughput

0.776

High

657177

PP12
Serine/threonine-protein phosphatase PP1-2

2

6

High-throughput

0.628

High

657190

PIG2
GSY2-interacting protein PIG2

2

11

High-throughput

0.611

High

523105

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.552

High

364342

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.536

High

543866

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.536

High

602321

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.536

High

657175

HRR25
Casein kinase I homolog HRR25

1

1

High-throughput

0.536

High

657193

PCL10
PHO85 cyclin-10

1

3

High-throughput

0.536

High

657195

FMP48
Probable serine/threonine-protein kinase FMP48

1

3

High-throughput

0.536

High

657201

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

4

High-throughput

0.536

High

657205

PCL8
PHO85 cyclin-8

1

3

High-throughput

0.536

High

657198

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.513

High

446208

PHSG
Glycogen phosphorylase

1

2

High-throughput

0.479

High

578880

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

657172

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

11

High-throughput

0.479

High

657173

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.479

High

657179

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

657181

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.479

High

657197

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

657202

GDE
Glycogen debranching enzyme

1

1

High-throughput

0.479

High

657204

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

392262

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

525959

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

657176

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

657184

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

1

High-throughput

0.445

High

657189

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

657174

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

657183

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

657187

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

657188

GIP2
GLC7-interacting protein 2

1

11

High-throughput

0.437

High

653821

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

657180

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

657192

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

657196

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

657170

SIS1
Protein SIS1

1

2

High-throughput

0.407

High

657194

YGI1
Uncharacterized protein YGL081W

1

0

High-throughput

0.279

Low

657178

EMP24
Endosomal protein P24B

1

0

High-throughput

0.269

Low

657199

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.249

Low

657200

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

657185

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

657186

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

657203

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025