Interactor 1: EDN3 (P14138)
Endothelin-3 (ET-3) (Preproendothelin-3) (PPET3)
Gene: EDN3
Interactor 2: EDNRB (P24530)
Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type)
Gene: EDNRB
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 7509919 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Endothelin |
| Common GO terms | GO:0001755 - neural crest cell migration GO:0007166 - cell surface receptor signaling pathway GO:0008284 - positive regulation of cell population proliferation GO:0014826 - vein smooth muscle contraction GO:0030318 - melanocyte differentiation and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
