Protein: EDNRB
Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type)

Gene: EDNRB
Organism: Homo sapiens
Interactions: 38
UniProt ID: P24530

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001755 - neural crest cell migration
GO:0002001 - renin secretion into blood stream
GO:0002027 - regulation of heart rate
GO:0004962 - endothelin receptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

570649

EDN3
Endothelin-3

1

2

Small-scale

0.647

High

665307

KNTC1
Kinetochore-associated protein 1

2

2

High-throughput

0.628

High

665308

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

20

High-throughput

0.628

High

665320

PXK
PX domain-containing protein kinase-like protein

2

3

High-throughput

0.628

High

665322

CIP2A
Protein CIP2A

2

5

High-throughput

0.628

High

665325

EXOC2
Exocyst complex component 2

2

3

High-throughput

0.628

High

665330

LCAP
Leucyl-cystinyl aminopeptidase

2

4

High-throughput

0.628

High

427008

EDN1
Endothelin-1

1

2

Small-scale

0.618

High

665305

ARBK1
Beta-adrenergic receptor kinase 1

1

11

Small-scale

0.618

High

665306

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

20

Small-scale

0.618

High

137184

EXOC5
Exocyst complex component 5

2

2

High-throughput

0.574

High

173657

BTAF1
TATA-binding protein-associated factor 172

2

5

High-throughput

0.574

High

665311

ATM
Serine-protein kinase ATM

2

14

High-throughput

0.574

High

665317

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

3

High-throughput

0.574

High

665318

THADA
tRNA

2

3

High-throughput

0.574

High

665324

INT12
Integrator complex subunit 12

2

2

High-throughput

0.574

High

665326

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

3

High-throughput

0.574

High

665329

XPO7
Exportin-7

2

16

High-throughput

0.574

High

665331

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

2

9

High-throughput

0.574

High

665332

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

2

9

High-throughput

0.574

High

665309

CAV1
Caveolin-1

1

4

Small-scale

0.561

High

164529

TNPO2
Transportin-2

2

3

High-throughput

0.558

High

164257

NRP1
Neuropilin-1

1

3

High-throughput

0.536

High

565557

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

19

High-throughput

0.536

High

665327

EXOC1
Exocyst complex component 1

1

2

High-throughput

0.536

High

230694

NKG2F
NKG2-F type II integral membrane protein

1

2

High-throughput

0.489

High

252829

EXOC3
Exocyst complex component 3

1

3

High-throughput

0.489

High

665314

ECM29
Proteasome adapter and scaffold protein ECM29

1

10

High-throughput

0.489

High

665315

F91A1
Protein FAM91A1

1

1

High-throughput

0.489

High

665316

TYW1B
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B

1

2

High-throughput

0.489

High

665319

MMS22
Protein MMS22-like

1

2

High-throughput

0.489

High

665328

IPO11
Importin-11

1

9

High-throughput

0.489

High

665323

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.479

High

665313

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

2

High-throughput

0.470

High

550846

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

665310

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

3

Small-scale

0.437

High

665312

Q4LE60
TNPO2 variant protein

1

3

High-throughput

0.407

High

665321

VPS8
Vacuolar protein sorting-associated protein 8 homolog

2

0

High-throughput

0.328

High


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Last updated: 11Aug2025