Protein: EDNRA
Endothelin-1 receptor (Endothelin receptor type A) (ET-A) (ETA-R) (hET-AR)

Gene: EDNRA
Organism: Homo sapiens
Interactions: 50
UniProt ID: P25101

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001666 - response to hypoxia
GO:0001701 - in utero embryonic development
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

427009

EDN1
Endothelin-1

2

2

Small-scale

0.768

High

669182

ARRB2
Beta-arrestin-2

1

17

Small-scale

0.691

High

669184

ARRB1
Beta-arrestin-1

1

17

Small-scale

0.691

High

669189

MTX1
Metaxin-1

3

8

High-throughput

0.667

High

219600

B2L11
Bcl-2-like protein 11

3

0

High-throughput

0.638

High

669181

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

15

Small-scale

0.618

High

360251

COX1
Cytochrome c oxidase subunit 1

2

4

High-throughput

0.611

High

397577

NU1M
NADH-ubiquinone oxidoreductase chain 1

2

1

High-throughput

0.611

High

669199

LMBR1
Limb region 1 protein homolog

2

1

High-throughput

0.611

High

226401

SNG2
Synaptogyrin-2

3

3

High-throughput

0.609

High

669192

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

3

1

High-throughput

0.609

High

669204

ARL5B
ADP-ribosylation factor-like protein 5B

3

5

High-throughput

0.609

High

261086

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.536

High

281562

MTX2
Metaxin-2

1

8

High-throughput

0.536

High

321744

AGRL1
Adhesion G protein-coupled receptor L1

1

8

High-throughput

0.536

High

551953

ADT1
ADP/ATP translocase 1

1

9

High-throughput

0.536

High

565559

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

18

High-throughput

0.536

High

669185

CAV2
Caveolin-2

1

4

High-throughput

0.536

High

669186

BI1
Bax inhibitor 1

1

5

High-throughput

0.536

High

669187

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.536

High

669194

AN13A
Ankyrin repeat domain-containing protein 13A

1

2

High-throughput

0.536

High

669196

TM87A
Transmembrane protein 87A

1

2

High-throughput

0.536

High

669207

T126A
Transmembrane protein 126A

1

3

High-throughput

0.536

High

669210

PIGU
GPI-anchor transamidase component PIGU

1

1

High-throughput

0.536

High

669198

HDAC7
Histone deacetylase 7

1

1

Small-scale

0.523

High

669200

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.523

High

557104

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

Small-scale

0.515

High

166865

MGST3
Glutathione S-transferase 3, mitochondrial

1

1

High-throughput

0.489

High

276945

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

1

High-throughput

0.489

High

664943

ERD21
ER lumen protein-retaining receptor 1

1

3

High-throughput

0.489

High

669183

ERD22
ER lumen protein-retaining receptor 2

1

3

High-throughput

0.489

High

669191

OXA1L
Mitochondrial inner membrane protein OXA1L

1

2

High-throughput

0.489

High

669193

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

4

High-throughput

0.489

High

669197

ZNT7
Zinc transporter 7

1

4

High-throughput

0.489

High

669202

RN185
E3 ubiquitin-protein ligase RNF185

1

4

High-throughput

0.489

High

669203

RUSF1
RUS family member 1

1

1

High-throughput

0.489

High

669205

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

8

High-throughput

0.489

High

669206

PTSS2
Phosphatidylserine synthase 2

1

3

High-throughput

0.489

High

669208

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.489

High

669211

REEP4
Receptor expression-enhancing protein 4

1

3

High-throughput

0.489

High

669212

XPO5
Exportin-5

1

15

High-throughput

0.489

High

669195

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

2

High-throughput

0.479

High

669190

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.426

High

506553

GPHRB
Golgi pH regulator B

1

7

High-throughput

0.407

High

669209

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

3

Small-scale

0.407

High

669214

XPO7
Exportin-7

1

17

High-throughput

0.407

High

669188

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

3

0

High-throughput

0.347

High

669201

KAT5
Histone acetyltransferase KAT5

1

0

Small-scale

0.299

High

322004

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.279

Low

669213

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025