Interactor 1: FPPS (P14324)
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Gene: FDPS
Interactor 2: FPPS (P14324)
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Gene: FDPS
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16684881 |
| Identification Methods | x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | polyprenyl_synt~polyprenyl_synt |
| Common GO terms | GO:0003723 - RNA binding GO:0004161 - dimethylallyltranstransferase activity GO:0004337 - (2E,6E)-farnesyl diphosphate synthase activity GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 7 others more... |
| Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc |  |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Hp | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
